Medicinal Chemistry
Utilizing medicinal chemistry principles for hit-to-lead and lead optimization, WuXi AppTec designs and synthesizes analogs as well as focused libraries in collaboration with our client’s medicinal chemistry.
Integrated Medicinal Chemistry Platform
Seamless collaboration of medicinal chemistry,
computational biology, in vivo pharmacology DMPK, and
toxicology to efficiently and cost-effectively move our
client’s drug discovery projects to candidate nomination,
preclinical development, and IND.
Extensive computational capabilities; crystallography
services; in house crystallographer.
SAR generation and pharmaceutical property
optimization to preclinical candidate selection.
Numerous programs across major target classes and indications
31 Programs since mid-2008: 27 large pharma/biotech,
3 medium pharma, 2 VC/virtual.
Program goals met; milestones achieved to advance
programs to next stage.
